Intensive care medicine
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Intensive care medicine · Jul 2005
ReviewStudying outcomes of intensive care unit survivors: the role of the cohort study.
As research focuses on long-term patient outcomes and the "real world" effectiveness of intensive care unit (ICU) therapies, the cohort study is increasingly being used in critical care research. ⋯ We make recommendations for the design of future cohort studies to maximize the impact of this research in improving the long-term outcomes of critically ill patients.
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Intensive care medicine · Jul 2005
Randomized Controlled Trial Clinical TrialA pilot study of inhaled nitric oxide in preterm infants treated with nasal continuous positive airway pressure for respiratory distress syndrome.
To explore the acute effects of inhaled nitric oxide (iNO) on oxygenation, respiratory rate, and CO2 levels in spontaneously breathing preterm infants treated with nasal continuous positive airway pressure (nCPAP) for moderate respiratory distress syndrome (RDS). ⋯ Adding 10 ppm nitric oxide to nasal CPAP treatment in preterm infants suffering from RDS results in a moderate but statistically significant improvement in oxygenation, with no effect on respiratory drive or systemic circulatory parameters.
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Intensive care medicine · Jul 2005
Review Meta AnalysisImpact of selective decontamination of the digestive tract on fungal carriage and infection: systematic review of randomized controlled trials.
To determine the impact of the antifungal component of selective decontamination of the digestive tract on fungal carriage, infection and fungaemia. ⋯ Antifungals, as part of selective decontamination of the digestive tract, reduce fungal carriage and infection but not fungaemia in critically ill patients and may justify the inclusion of an antifungal component in the decontamination protocol.
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Intensive care medicine · Jul 2005
Randomized Controlled Trial Clinical TrialErythromycin dose of 70 mg accelerates gastric emptying as effectively as 200 mg in the critically ill.
To compare the effectiveness of 70-mg and 200-mg doses of intravenous erythromycin in improving gastric emptying in critically ill patients. ⋯ Treatment with 70 and 200 mg intravenous erythromycin are equally effective in accelerating gastric emptying in the critically ill.