Intensive care medicine
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Intensive care medicine · Apr 2012
Time course of metabolic activity and cellular infiltration in a murine model of acid-induced lung injury.
This study investigates whether positron emission tomography (PET) can be used to monitor the inflammatory response and its correlation with the later fibroproliferative phase in an experimental model of acute lung injury. ⋯ This study demonstrated that PET imaging is a valid means of tracking the inflammatory response, also in longitudinal studies. Moreover, a correlation was found between persistence of the inflammatory response and fibrotic evolution of the injury.