Intensive care medicine
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Intensive care medicine · Apr 2012
Peripheral vasoconstriction influences thenar oxygen saturation as measured by near-infrared spectroscopy.
Near-infrared spectroscopy has been used as a noninvasive monitoring tool for tissue oxygen saturation (StO(2)) in acutely ill patients. This study aimed to investigate whether local vasoconstriction induced by body surface cooling significantly influences thenar StO(2) as measured by InSpectra model 650. ⋯ Peripheral vasoconstriction due to body surface cooling could significantly influence noninvasive measurements of thenar StO(2) using InSpectra model 650 with 15-mm probe spacing.
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Intensive care medicine · Apr 2012
Time course of metabolic activity and cellular infiltration in a murine model of acid-induced lung injury.
This study investigates whether positron emission tomography (PET) can be used to monitor the inflammatory response and its correlation with the later fibroproliferative phase in an experimental model of acute lung injury. ⋯ This study demonstrated that PET imaging is a valid means of tracking the inflammatory response, also in longitudinal studies. Moreover, a correlation was found between persistence of the inflammatory response and fibrotic evolution of the injury.