Intensive care medicine
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Intensive care medicine · May 2015
Review Meta Analysis Comparative StudyAssessment of impairment and activity limitations in the critically ill: a systematic review of measurement instruments and their clinimetric properties.
To identify measures used to evaluate the broad constructs of functional impairment and limitations in the critically ill across the continuum of recovery, and to evaluate, synthesise and compare the clinimetric properties of the measures identified. ⋯ There is considerable variability in the type of measures utilized to measure physical impairments and limitations in survivors of critical illness. Future work should identify a core set of standardized measures, which can be utilized across the continuum of critical illness recovery embedded within the International Classification of Functioning framework. This will enable improved comparisons between future studies, which in turn will assist in identifying the most effective treatment strategies to ameliorate the devastating longer-term outcomes of a critical illness.
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Intensive care medicine · May 2015
Randomized Controlled Trial Comparative StudyEarly physical rehabilitation in intensive care patients with sepsis syndromes: a pilot randomised controlled trial.
Survivors of sepsis syndromes have poor outcomes for physical and cognitive function. No investigations of early physical rehabilitation in the intensive care unit have specifically targeted patients with sepsis syndromes. ⋯ Implementation of early physical rehabilitation can improve self-reported physical function and induce systemic anti-inflammatory effects.
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Intensive care medicine · May 2015
Comparative StudyImpact of early nutrition and feeding route on outcomes of mechanically ventilated patients with shock: a post hoc marginal structural model study.
Few data are available about optimal nutrition modalities in mechanically ventilated patients with shock. Our objective was to assess associations linking early nutrition (<48 h after intubation), feeding route and calorie intake to mortality and risk of ventilator-associated pneumonia (VAP) in patients with invasive mechanical ventilation (IMV) and shock. ⋯ In mechanically ventilated patients with shock, early nutrition was associated with reduced mortality. Neither feeding route nor early calorie intake was associated with mortality. Early nutrition and enteral feeding were associated with increased VAP risk.