Intensive care medicine
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Intensive care medicine · Dec 2016
Observational StudyThe effect of sepsis and its inflammatory response on mechanical clot characteristics: a prospective observational study.
Sepsis and its progression are known to have a major influence on the coagulation system. Current coagulation tests are of limited use when assessing coagulation in sepsis patients. This study aims to assess the potential for a new functional biomarker of clot microstructure, fractal dimension, to identify changes in the mechanical properties of clot microstructure across the sepsis spectrum (sepsis, severe sepsis and septic shock). ⋯ This study confirms that clot microstructure is significantly altered through the various stages of sepsis. Of particular importance was the marked change in clot development between severe sepsis and septic shock, which has not been previously reported.
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Intensive care medicine · Dec 2016
Letter Multicenter Study Comparative StudyComparison of the qSOFA and CRB-65 for risk prediction in patients with community-acquired pneumonia.
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Intensive care medicine · Dec 2016
Letter Multicenter Study Observational StudyCAST: a new score for early prediction of neurological outcomes after cardiac arrest before therapeutic hypothermia with high accuracy.