Intensive care medicine
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Intensive care medicine · Mar 2016
Cytomegalovirus reactivation and mortality in patients with acute respiratory distress syndrome.
Cytomegalovirus (CMV) reactivation occurs frequently in patients with the acute respiratory distress syndrome (ARDS) and has been associated with increased mortality. However, it remains unknown whether this association represents an independent risk for poor outcome. We aimed to estimate the attributable effect of CMV reactivation on mortality in immunocompetent ARDS patients. ⋯ CMV reactivation is independently associated with increased case fatality in immunocompetent ARDS patients who are CMV seropositive.
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Intensive care medicine · Mar 2016
Observational StudyChronic antiplatelet therapy is not associated with alterations in the presentation, outcome, or host response biomarkers during sepsis: a propensity-matched analysis.
Sepsis is a major health burden worldwide. Preclinical investigations in animals and retrospective studies in patients have suggested that inhibition of platelets may improve the outcome of sepsis. In this study we investigated whether chronic antiplatelet therapy impacts on the presentation and outcome of sepsis, and the host response. ⋯ Pre-existing antiplatelet therapy is not associated with alterations in the presentation or outcome of sepsis, or the host response.
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Intensive care medicine · Mar 2016
Ultrasound-guided percutaneous dilational tracheostomy versus bronchoscopy-guided percutaneous dilational tracheostomy in critically ill patients (TRACHUS): a randomized noninferiority controlled trial.
Percutaneous dilational tracheostomy (PDT) is routinely performed in the intensive care unit with bronchoscopy guidance. Recently, ultrasound has emerged as a potentially useful tool to assist PDT and reduce procedure-related complications. ⋯ Ultrasound-guided PDT is noninferior to bronchoscopy-guided PDT in mechanically ventilated critically ill patients.
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Intensive care medicine · Mar 2016
Letter Observational StudySkin mottling score as a predictor of 28-day mortality in patients with septic shock.