Intensive care medicine
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Intensive care medicine · May 1997
Randomized Controlled Trial Multicenter Study Clinical TrialSaccharomyces boulardii prevents diarrhea in critically ill tube-fed patients. A multicenter, randomized, double-blind placebo-controlled trial.
To assess the preventive effect of Saccharomyces boulardii on diarrhea in critically ill tube-fed patients and to evaluate risk factors for diarrhea. ⋯ S. boulardii prevents diarrhea in critically ill tube-fed patients, especially in patients with risk factors for diarrhea.
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Intensive care medicine · May 1997
Randomized Controlled Trial Clinical TrialGastrointestinal permeability following cardiopulmonary bypass: a randomised study comparing the effects of dopamine and dopexamine.
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Intensive care medicine · Apr 1997
Randomized Controlled Trial Clinical TrialUnfavorable mechanical effects of heat and moisture exchangers in ventilated patients.
To investigate the mechanical effects of artificial noses. ⋯ The artificial noses cause unfavorable mechanical effects by increasing inspiratory resistance, ventilation requirements, and dynamic intrinsic PEEP. Clinicians should consider these effects when setting mechanical ventilation and when assessing patients' ability to breathe spontaneously.
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Intensive care medicine · Apr 1997
Randomized Controlled Trial Clinical TrialUse of 2% propofol to produce diurnal sedation in critically ill patients.
The assessment of propofol to produce diurnal sedation in critically ill patients. ⋯ Propofol can safely provide diurnal sedation in the critically ill when titrated against the Ramsay score. Sedation levels cannot be manipulated in some severely ill patients.
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Intensive care medicine · Mar 1997
Randomized Controlled Trial Clinical TrialInfluence of enoximone on systemic and splanchnic oxygen utilization and endotoxin release following cardiopulmonary bypass.
We investigated whether the administration of enoximone during and after cardiopulmonary bypass (CPB) improves splanchnic oxygen utilization and thereby gut mucosal integrity in humans by its vasodilating and inotropic properties. ⋯ Improvement of oxygen delivery by enoximone did not prevent gastric mucosal acidosis following CPB. However, since the increase in endotoxin levels in liver venous blood was diminished by using enoximone, the drug seems to have a beneficial effect on tissue damage and barrier function of the gut.