Intensive care medicine
-
Intensive care medicine · May 1995
Randomized Controlled Trial Clinical TrialRespiratory mechanics by least squares fitting in mechanically ventilated patients: applications during paralysis and during pressure support ventilation.
To evaluate a least squares fitting technique for the purpose of measuring total respiratory compliance (Crs) and resistance (Rrs) in patients submitted to partial ventilatory support, without the need for esophageal pressure measurement. ⋯ The LSF method allows non-invasive evaluation of respiratory mechanics during PSV, provided that a near-relaxation condition is obtained by means of an adequately increased pressure support level. The measurement of P0.1 may be helpful for titrating the pressure support in order to obtain the condition of near-relaxation.
-
Intensive care medicine · Mar 1995
Randomized Controlled Trial Comparative Study Clinical TrialEffects of inhaled nitric oxide on right ventricular function in severe acute respiratory distress syndrome.
To compare the effects of inhaled nitric oxide (NO) and an infusion of prostacyclin (PGI2) on right ventricular function in patients with severe acute respiratory distress syndrome (ARDS). ⋯ Using a new approach to selective pulmonary vasodilation by inhalation of NO, we demonstrate in this group of ARDS patients that an increase in RVEF is not necessarily associated with a rise in CI. The increase in CI during PGI2 infusion is probably related to the systemic effect of this substance.
-
Intensive care medicine · Nov 1994
Randomized Controlled Trial Clinical TrialContribution of non-neurologic disturbances in acute physiology to the prediction of intensive care outcome after head injury or non-traumatic intracranial haemorrhage.
To study the additional contribution of non-neurologic disturbances in acute physiology and chronic health to the prediction of intensive care outcome in patients with head injury or non-traumatic intracranial haemorrhage. ⋯ The non-neurologic disturbances in acute physiology have prognostic significance in the prediction of intensive care outcome in patients with head injury or non-traumatic intracerebral haemorrhage. The created predictive model may supplement clinical judgement of this patient group.
-
Intensive care medicine · Nov 1994
Randomized Controlled Trial Clinical TrialUse of antithrombin III in critical patients.
To evaluate the effect of the AT III concentrates upon the clinical evolution and hemostatic parameters. ⋯ The results suggest that the administration of AT III concentrates to critical patients with acquired low levels, but without manifest DIC, may not be justified; although further studies on a larger population are required to establish definite conclusions.
-
Intensive care medicine · Aug 1994
Randomized Controlled Trial Comparative Study Clinical TrialAccuracy assessment for three fiberoptic pulmonary artery catheters for SvO2 monitoring.
To compare values of SvO2 obtained by reflectance spectrophotometry continuous monitoring with those obtained from blood samples measurements by transmission spectrophotometry (Co-Oximetry). ⋯ For usual monitoring in the ICU, SAT2 and OX3, gave SvO2 values which are in acceptable agreement with SvO2 measured on blood samples by Co-Oximetry.