Intensive care medicine
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Intensive care medicine · Mar 2002
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialEvaluation of patient skin breakdown and comfort with a new face mask for non-invasive ventilation: a multi-center study.
To evaluate patient comfort, skin breakdown and eye irritation when comparing a prototype face mask (PM) and conventional face masks (CMs) during non-invasive ventilation. ⋯ The PM significantly reduced skin breakdown while improving patient comfort, compared to the CMs.
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Intensive care medicine · Feb 2002
Randomized Controlled Trial Clinical TrialPhysiological effects of constant versus decelerating inflation flow in patients with chronic obstructive pulmonary disease under controlled mechanical ventilation.
To study the cardiorespiratory effects of inspiratory flow rate and waveform in COPD patients. ⋯ Changing the ventilator in volume-controlled mode with a DF or CF profile has no significant cardiorespiratory effect in intubated COPD patients mechanically ventilated for acute respiratory failure.
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Intensive care medicine · Feb 2002
Randomized Controlled Trial Comparative Study Clinical TrialImpact of sepsis, lung injury, and the role of lipid infusion on circulating prostacyclin and thromboxane A(2).
To investigate whether plasma levels of prostacyclin (PGI2) and thromboxane A(2) (TxA2) are a function of the infusion rate of soybean-based fat emulsions, severity of systemic inflammation, and pulmonary organ failure. ⋯ The quantity of prostanoids formed and their subsequent utilization are dependent on the availability of precursor linoleic acid and are probably affected by the severity of SIRS or sepsis and the existence of pulmonary organ failure, respectively. Because TxA2 might be extracted by the injured lung, rapid infusion of soybean-based fat emulsions should be avoided in patients suffering from severe pulmonary organ failure.
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Intensive care medicine · Jan 2002
Randomized Controlled Trial Comparative Study Clinical TrialThe use of the laryngeal mask airway as an alternative to the endotracheal tube during percutaneous dilatational tracheostomy.
To evaluate the safety and efficiency of the use of the laryngeal mask airway (LMA) during percutaneous dilatational tracheostomy under bronchoscopic guidance comparing with the ventilation via endotracheal tube (ET). ⋯ LMA is an effective and successful ventilatory device during percutaneous dilatational tracheostomy. It improves visualization of the trachea and larynx during fiberoptic-assisted percutaneous dilatational tracheostomy and prevents the difficulties associated with the use of ET such as cuff puncture, tube transection by the needle, and accidental extubation. The use of a bronchoscope and the puncture of the ET cuff cause major increases in PaCO2.
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Intensive care medicine · Jan 2002
Randomized Controlled Trial Comparative Study Clinical TrialProne positioning, systemic hemodynamics, hepatic indocyanine green kinetics, and gastric intramucosal energy balance in patients with acute lung injury.
To investigate the effects of prone positioning on systemic hemodynamics, intra-abdominal pressure (IAP), plasma disappearance rate of indocyanine green (PDR(ICG)), and gastric intramucosal to arterial PCO2 difference (Pi-aCO2). ⋯ Prone positioning in mechanically ventilated patients with acute lung injury, despite a small increase in IAP, does not negatively affect the hepatic capacity to eliminate ICG and gastric intramucosal energy balance when systemic blood flow and oxygenation are improved.