The American journal of medicine
-
Randomized Controlled Trial
Treatment-Resistant Hypertension and Outcomes Based on Randomized Treatment Group in ALLHAT.
Although hypertension guidelines define treatment-resistant hypertension as blood pressure uncontrolled by ≥3 antihypertensive medications, including a diuretic, it is unknown whether patient prognosis differs when a diuretic is included. ⋯ In this study, which titrated medications to a goal, participants assigned to chlorthalidone were less likely to develop treatment-resistant hypertension. However, prognoses in those with treatment-resistant hypertension were similar across treatment groups.
-
Editorial Comment
Salt, Tomato Soup, and the Hypocrisy of the American Heart Association.