Journal of the Royal Society of Medicine
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Review Meta Analysis
Income and child mortality in developing countries: a systematic review and meta-analysis.
We aimed to quantify the relationship between national income and infant and under-five mortality in developing countries. ⋯ Income is an important determinant of child survival and this work provides a pooled estimate for the relationship.
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Review Meta Analysis
A systematic review and meta-analysis of the cardioprotective effects of remote ischaemic preconditioning in open cardiac surgery.
To investigate the cardioprotective efficacy of remote ischaemic preconditioning (RIPC) in cardiac surgery. ⋯ Although our analysis suggests RIPC may result in cardiac protection during cardiac surgery, the effect was most marked in studies without full blinding, with a smaller and statistically non-significant effect in fully blinded studies. We propose that further double blind randomized controlled trials investigating the cardioprotective effects of RIPC in cardiac surgery are required to resolve the current clinical uncertainty.
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Review Meta Analysis
Risk of cardiovascular events and celecoxib: a systematic review and meta-analysis.
To examine whether the increased risk of cardiovascular events with rofecoxib represents a class effect of cyclooxygenase-2 (COX-2) specific inhibitors. ⋯ The available data indicate an increased risk of myocardial infarction with celecoxib therapy, consistent with a class effect for COX-2 specific inhibitors.