Journal of the Royal Society of Medicine
-
Randomized Controlled Trial Comparative Study Clinical Trial
Atropine or glycopyrrolate with neostigmine 5 mg: a comparative dose-response study.
One hundred and fifteen patients, separated into 4 groups, received neostigmine 5 mg with either atropine 1.2 mg or 1.8 mg, or glycopyrrolate 0.6 mg or 0.9 mg. Those receiving 0.9 mg glycopyrrolate had insignificant changes in heart rate in the immediate postreversal period. It is recommended that when glycopyrrolate is used with 5 mg neostigmine, the optimum dose is 0.9 mg.
-
Randomized Controlled Trial Clinical Trial
Posture and lumbar puncture headache: a controlled trial in 50 patients.
A prospective single blind trial in 50 patients was performed to investigate the effect of posture on post lumbar puncture headache (LPH). A difference between the frequency of headache at five hours between the two groups (prone for four hours, versus 30 degrees head down tilt for 30 minutes followed by supine posture for 3 1/2 hours) did not reach significance. ⋯ The value of bed rest after lumbar puncture remains equivocal. Other methods used for reducing LPH are reviewed.