Neurosurgery
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We report a case of the anomalous exit of the C-6 nerve root at the C-6, C-7 foramen. This caused intense radicular and cervical pain in a 25-year-old woman. At myelography, the 5th and 6th cervical roots appeared conjoined, and at operation the C-6 root and ganglion were found to turn acutely downward, lateral to the pedicle of C-6, and then to exit with the C-7 nerve root through the C-6, C-7 foramen. ⋯ Cervical hemilaminectomy and resection of the pedicle of C-6 defined the anatomy and resulted in a clinical cure. The radiological features are described and contrasted with those of other anomalies. To our knowledge, this is the first report of such an anomalous course of exit of a cervical root.
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Visual loss due to optic nerve injury after closed head trauma constitutes a formidable diagnostic and therapeutic challenge for the clinician. Assessment must be made of the site of optic nerve injury, and this is often difficult in the patient with an altered level of consciousness. A decision regarding optic nerve decompression must be formulated, yet the literature is confusing with regard to operative indications. In reviewing current pathogenetic theories, clinicopathological data, and therapeutic options, this report attempts to clarify the role of surgical intervention in indirect optic nerve injury.
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Biography Historical Article
Innovation in neurosurgery: Walter Dandy in his day.
In 1925, Walter Dandy published a preliminary report of an innovative operative procedure for patients with tic douloureux. Dandy reported treating tic by selectively sectioning the trigeminal nerve at the brain stem. His operative field was the cerebellopontine angle, which he exposed using a cerebellar approach. ⋯ This article examines historically Doctor Dandy's ideas regarding the treatment of tic and evaluates them within the context of the emerging development of the profession of neurological surgery from 1920 to 1945. It documents that his operative approach was accepted and used among an elite group of neurosurgeons. It also discusses political, personal, social, and technological issues that contributed to the overall rejection of the Dandy procedure.
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Fifty-two patients were each given a constant infusion of 1.5 g of epsilon-aminocaproic acid (EACA) per hour after subarachnoid hemorrhage (SAH) from an intracranial aneurysm. Each patient's available plasminogen activity (APA), a measure of plasma fibrinolytic activity, was determined by fluorometric assay before and during EACA treatment. Five categories of potential EACA complications were identified: rebleeding, cerebral vasospasm, hydrocephalus, thrombosis, and miscellaneous (bleeding time prolongation, thrombocytopenia). ⋯ It is apparent from these studies that, after the initiation of EACA treatment, a maximal steady state inhibition of fibrinolytic activity is not achieved for 2 days and, after the cessation of EACA therapy, normal fibrinolytic activity is not restored for a period of 3 to 4 days. In addition, patients with thrombotic events may show persistently low serum plasminogen activity after discontinuance of EACA therapy, probably due to continuing thrombosis and consumption of plasminogen. These results indicate that patients with recurrent preoperative aneurysmal hemorrhage while on EACA therapy may have inadequate fibrinolytic inactivation, and this may be an important factor contributing to rebleeding episodes.(ABSTRACT TRUNCATED AT 250 WORDS)