Sleep
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Randomized Controlled Trial
Behavioral treatment of chronic insomnia in older adults: does nocturia matter?
To evaluate the impact of nocturia on the therapeutic response of chronic insomnia to behavioral treatment in older adults. ⋯ These secondary analyses suggest that brief behavioral treatment of insomnia may be more efficacious in improving insomnia in participants without nocturia. Addressing nocturia may improve the efficacy of behavioral insomnia treatment.
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Randomized Controlled Trial
Evaluation of a brief treatment program of cognitive behavior therapy for insomnia in older adults.
To evaluate the efficacy of a brief 4-w group-administered treatment program of cognitive behavior therapy for insomnia (CBT-I) for older adults with sleep maintenance insomnia. ⋯ The treatment program used in the current study has demonstrated potential for a brief, inexpensive, and effective treatment of sleep maintenance insomnia in the older adult population.
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Randomized Controlled Trial Multicenter Study Observational Study
Predictors of long-term adherence to continuous positive airway pressure therapy in patients with obstructive sleep apnea and cardiovascular disease in the SAVE study.
To determine the clinical variables that best predict long- term continuous positive airway pressure (CPAP) adherence among patients with cardiovascular disease who have obstructive sleep apnea (OSA). ⋯ Clinical Trials, http://www.clinicaltrials.gov, NCT00738179.
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Randomized Controlled Trial Multicenter Study
Effectiveness of three sleep apnea management alternatives.
Home respiratory polygraphy (HRP) may be a cost-effective alternative to polysomnography (PSG) for diagnosis and treatment election in patients with high clinical probability of obstructive sleep apnea (OSA), but there is conflicting evidence on its use for a wider spectrum of patients. ⋯ Home respiratory polygraphy is a less costly alternative than polysomnography for the diagnosis and therapeutic decision making for patients with suspected obstructive sleep apnea. We found no advantage in cost terms, however, in using home respiratory polygraphy for all patients or home respiratory polygraphy for the most symptomatic patients and polysomnography for the rest.
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Randomized Controlled Trial Multicenter Study
Efficacy of vestipitant, a neurokinin-1 receptor antagonist, in primary insomnia.
Investigate the hypnotic effects of repeated doses of neurokinin-1 receptor antagonist, vestipitant, in primary insomnia. ⋯ Vestipitant improved sleep maintenance in patients with primary insomnia, with no associated next-day cognitive impairment. The effects on wake after sleep onset and total sleep time were maintained following repeated dosing.