Annals of emergency medicine
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To determine the predictive value of the rate of change of serial beta-human chorionic gonadotropin (hCG) values in patients with symptoms suggestive of ectopic pregnancy but who have indeterminate transvaginal ultrasound findings, and to determine whether the predictive value was enhanced depending on whether the endometrial cavity was empty at ultrasound examination. ⋯ The rate of change of serial beta-hCG values, in patients with an indeterminate pelvic ultrasound examination, is predictive of ectopic pregnancy. Addition of whether the endometrial cavity is empty at ultrasound leads to a further improvement in predictive accuracy.