Annals of emergency medicine
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Sulfonylurea agents are widely used as therapy for hyperglycemia in type 2 diabetes mellitus. In overdose, these agents can produce sustained and profound hypoglycemia that is refractory to treatment with dextrose alone. Our objective was to determine whether treatment with octreotide decreases glucose requirements and the number of hypoglycemic episodes in patients with sulfonylurea-induced hypoglycemia. ⋯ Octreotide appears to be safe and effective in preventing rebound hypoglycemia after sulfonylurea ingestion. Octreotide in combination with dextrose should be considered for first-line therapy in the treatment of sulfonylurea-induced hypoglycemia.
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[American College of Emergency Physicians. Domestic violence: the role of EMS personnel. Ann Emerg Med. August 2000;36:180.].
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[Sklar DP. Letting go. Ann Emerg Med. August 2000;36:167-168.].