European heart journal
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European heart journal · Dec 1995
Randomized Controlled Trial Clinical TrialFurther elevation of the ST segment during the first hour of thrombolysis. A possible early marker of reperfusion.
To evaluate the clinical implications of early electrocardiographic changes during thrombolysis in a randomized study in patients with an acute myocardial infarction. ⋯ Additional ST segment elevation is frequently observed during the first hour of intravenous thrombolysis with streptokinase. Its' association with a subsequent early decline of ST elevation, reduced mortality, a shorter time interval to peak creatine kinase, and a high rate of late recanalization, suggest that in some patients it is one of the earliest markers of reperfusion.