European heart journal
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European heart journal · Sep 2014
Randomized Controlled Trial Multicenter Study Comparative StudyPrasugrel plus bivalirudin vs. clopidogrel plus heparin in patients with ST-segment elevation myocardial infarction.
Whether prasugrel plus bivalirudin is a superior strategy to unfractionated heparin plus clopidogrel in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) has never been assessed in specifically designed randomized trials. ⋯ Unique identifier NCT00976092 (www.clinicaltrials.gov).
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European heart journal · Sep 2014
Multicenter Study Comparative Study Observational StudyDirect comparison of high-sensitivity-cardiac troponin I vs. T for the early diagnosis of acute myocardial infarction.
It is unknown whether cardiac troponin (cTn) I or cTnT is the preferred biomarker in the early diagnosis of acute myocardial infarction without ST segment elevation (NSTEMI). ⋯ Both hs-cTnI and hs-cTnT provided high diagnostic and prognostic accuracy. The direct comparison revealed small but potentially important differences that might help to further improve the clinical use of hs-cTn.