European heart journal
-
European heart journal · Mar 2015
Randomized Controlled Trial Multicenter StudyBeneficial effects of long-term intravenous iron therapy with ferric carboxymaltose in patients with symptomatic heart failure and iron deficiency†.
The aim of this study was to evaluate the benefits and safety of long-term i.v. iron therapy in iron-deficient patients with heart failure (HF). ⋯ Treatment of symptomatic, iron-deficient HF patients with FCM over a 1-year period resulted in sustainable improvement in functional capacity, symptoms, and QoL and may be associated with risk reduction of hospitalization for worsening HF (ClinicalTrials.gov number NCT01453608).
-
European heart journal · Mar 2015
Editorial CommentIron i.v. in heart failure: ready for implementation?
-
European heart journal · Mar 2015
Review Meta AnalysisSystemic thrombolytic therapy for acute pulmonary embolism: a systematic review and meta-analysis.
Thrombolytic therapy induces faster clot dissolution than anticoagulation in patients with acute pulmonary embolism (PE) but is associated with an increased risk of haemorrhage. We reviewed the risks and benefits of thrombolytic therapy in the management of patients with acute PE. ⋯ Thrombolytic therapy reduces total mortality, PE recurrence, and PE-related mortality in patients with acute PE. The decrease in overall mortality is, however, not significant in haemodynamically stable patients with acute PE. Thrombolytic therapy is associated with an increase of major and fatal or intracranial haemorrhage.
-
European heart journal · Mar 2015
Editorial CommentExpression of concern relating to: D. Poldermans, E. Boersma, J. J. Bax, I. R. Thomson, B. Paelinck, L. L. M. van de Ven, M. G. Scheffer, G. Trocino, C. Vigna, H. F. Baars, H. van Urk, J. R. T. C. Roelandt, for the Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group. 'Bisoprolol reduces cardiac death and myocardial infarction in high-risk patients as long as 2 years after successful major vascular surgery'.
-
European heart journal · Mar 2015
Biography Historical ArticleCardioPulse: working in industry requires wanting to make medicines.