Preventive medicine
-
Preventive medicine · Mar 2021
Cervical screening in high-income countries: the need for quality assurance, adjunct biomarkers and rational adaptation to HPV vaccination.
We here discuss human papillomavirus (HPV)-based screening avenues to achieve elimination of cervical cancer as a public health problem in high-income country (HIC) settings, covering both the most recent data on the performance of HPV testing, as well as the currently most robust triage methods that are known. We also provide an outlook to several other promising, yet not fully established, options for triage that have been proposed, including methylation, dual staining, machine learning, and artificial intelligence. Finally, we discuss the key issue of how to adapt screening in the presence of programmatic HPV vaccination, and how this combination can best be leveraged for comprehensive cancer control. We conclude that, for the HIC setting, evidence-based and effective cervical screening methods are readily available, but whichever method or platform is chosen, we would propose that recurring audits of performance and population attendance remain common denominators for maintaining successful disease prevention.
-
Preventive medicine · Feb 2021
E-cigarette susceptibility among U.S. middle and high school students: National Youth Tobacco Survey Data Trend Analysis, 2014-2018.
Youth e-cigarette use has rapidly increased in the last few years. Susceptibility is a validated measure associated with future tobacco use. We examined trends in e-cigarette susceptibility across five years (2014-2018) of the National Youth Tobacco Survey among youth e-cigarette never users. ⋯ This study is the first to document trends in e-cigarette susceptibility among youth. Understanding antecedents of e-cigarette use and identifying youth subgroups vulnerable to e-cigarette use is valuable to developing effective prevention efforts. Disclaimer: The findings and conclusions in this publication are those of the authors and do not necessarily represent the official position of the Food and Drug Administration or the Centers for Disease Control and Prevention.
-
Preventive medicine · Feb 2021
Associations between e-cigarette pack size and vaping frequency among U.S. adults.
Little research exists on the association between e-cigarette pack quantity and use. We examined whether using e-cigarettes every day or somedays was associated with purchasing e-cigarettes by the box/pack or as singles. Data are from the 2018-2019 Tobacco Use Supplement to the Current Population Survey, analyzed in 2020. ⋯ Those who reported purchasing by the box/pack had greater odds of every day e-cigarette use compared to some day use (Adjusted Odds Ratio: 1.36, 95% CI: 1.09, 1.68). This finding held for both males, females, and all device types. These findings present a first step in determining the relationship between e-cigarette pack size and use behavior.