International journal of cardiology
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Letter Clinical Trial Observational Study
External validation of the GRACE Freedom from Events score in an emergency department 'rule out ACS' chest pain cohort.
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Letter Case Reports
Atrial flutter EKG can be useless without the proper electrophysiological basis.
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A meta-analysis was performed to evaluate the risk of major bleeding with the use of New Oral Anticoagulants (NOACs). ⋯ Risk of major bleeding with new oral anticoagulants varies with their indication for use. New agents may be associated with comparatively less major bleeding compared to VKA. NOAC may increase the risk of major bleeding after hip surgery, ACS and acute medically ill patients; but may be associated with less bleeding in treatment of acute VTE/PE.
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Observational Study
Flow-mediated dilation is associated with cardiovascular events in non-valvular atrial fibrillation patients.
Atrial fibrillation is associated with multiple atherosclerotic risk factors and predisposes to cardiovascular events (CVE). Endothelial dysfunction is associated with atherosclerosis and independently predicts CVE. The aim of the study was to evaluate the association between endothelial dysfunction, as assessed by flow-mediated dilation (FMD), and CVE in AF patients. ⋯ In AF patients low FMD is associated with increased risk of CVE suggesting that impaired artery dilatation predisposes to atherosclerotic complications.