Journal of pediatric gastroenterology and nutrition
-
J. Pediatr. Gastroenterol. Nutr. · Mar 2006
Neonatal herpes simplex virus infection presenting as acute liver failure: prevalent role of herpes simplex virus type I.
Acute liver failure (ALF) in neonates is rare but carries a high mortality without liver transplantation. Herpes simplex virus (HSV) is one of the microbes that more commonly causes ALF and is potentially treatable; hence, early diagnosis and treatment are important to avoid progression to liver failure. ⋯ HSV-related ALF in the neonatal period carries high morbidity and mortality and needs a high index of suspicion so that life-saving treatment can be started promptly. Both HSV-1 and HSV-2 can cause severe neonatal infection. It is important to recognise HSV infection in women of childbearing age and their sexual partners.
-
J. Pediatr. Gastroenterol. Nutr. · Jan 2006
Relationship of hepatic steatosis to adipose tissue distribution in pediatric nonalcoholic fatty liver disease.
Central adiposity, a component of insulin resistance syndrome, is a risk factor for nonalcoholic fatty liver disease (NAFLD) in adults. To determine whether a similar relationship occurs in children, hepatic fat content and adipose tissue distribution were assessed in obese children at risk for NAFLD. ⋯ Visceral adiposity is a risk factor for pediatric NAFLD.
-
J. Pediatr. Gastroenterol. Nutr. · Nov 2005
Randomized Controlled Trial Multicenter StudyDouble-blind randomized evaluation of clinical and biological tolerance of polyethylene glycol 4000 versus lactulose in constipated children.
To assess the safety of a polyethylene glycol (PEG) 4000 laxative without additional salts in pediatric patients. ⋯ This 3-month study in 96 constipated children aged 6 months to 3 years confirms the long-term tolerance of PEG 4000 in pediatrics and indicates a PEG efficacy similar to or greater than that of lactulose.
-
J. Pediatr. Gastroenterol. Nutr. · Sep 2005
Diagnosing functional abdominal pain with the Rome II criteria: parent, child, and clinician agreement.
To compare the Rome II diagnoses made in children with recurrent abdominal pain by physicians and by parent and child responses on the Questionnaire on Pediatric Gastrointestinal Symptoms. Rates of diagnostic agreement and reasons for disagreement were examined to determine whether changes to the Rome II criteria are needed to improve diagnostic classification. ⋯ The Rome II classification system shows promise for improving diagnosis, study and treatment of children with recurrent abdominal pain. However, further refinement and clarification of the Rome II criteria for symptom duration and frequency may be needed to improve diagnostic agreement.