Neuroepidemiology
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Patients with multiple sclerosis (MS) may have a higher risk of cardiovascular diseases (CVD) than the general population, but data are limited. ⋯ In this Danish cohort, the risk of CVD among MS patients was low, but greater than that in the general population, particularly in the short term.
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The prolonged length of stay (PLOS) score has recently been derived and validated in 2 independent national cohorts of acute stroke patients in Israel. The present study aimed to determine the performance of the PLOS score in an independent population-based cohort of stroke patients in a health care system considerably different from that in which the score was derived. ⋯ The PLOS score successfully predicted PLOS in the OXVASC population of acute stroke patients. Although the score was originally derived for the prediction of prolonged acute hospitalization, it successfully predicted prolonged total LOS.
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Black-white disparities in stroke mortality are well documented, but few recent studies have examined racial/ethnic disparities in stroke hospitalizations among young adults. We analyzed recent (2001-2006) trends in stroke hospitalizations and hospital case-fatality for black, Hispanic, and white adults aged 25-49 years in Florida. ⋯ Our study found a strong and persistent black-white disparity in stroke hospitalization rates for young adults. In contrast, rates were similar for Hispanics and whites. Multivariate adjustment explained the 15% excess case-fatality for blacks; the short-term mortality advantage among Hispanics was strengthened after adjustment.
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Multicenter Study Comparative Study
The time interval window between stroke onset and hospitalization and its related factors.
Successful acute stroke intervention depends on early hospitalization. The time interval between stroke onset to hospitalization was examined to identify the factors influencing the interval and also to determine whether treatment time window expansion will translate into more treatment. ⋯ Clinically more severe stroke patients were hospitalized earlier and nocturnal strokes had delayed admission. Even expanding the therapeutic time window from =3 to =6 h, there are possibilities that a substantial proportion of patients would not benefit from acute intervention. Future research should focus not only on developing therapies for expanding the treatment time window, but also place emphasis on reducing the interval between onset and hospitalization.