Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Sep 2011
Editorial CommentBotero's fat figures and the risk of heart failure.
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J. Am. Coll. Cardiol. · Sep 2011
Comparative StudyRapid exclusion of acute myocardial infarction in patients with undetectable troponin using a high-sensitivity assay.
This paper sought to evaluate whether high sensitivity troponin (hs-cTnT) can immediately exclude acute myocardial infarction (AMI) at a novel 'rule out' cut-off. ⋯ Undetectable hs-cTnT at presentation has very high negative predictive value, which may be considered to rule out AMI, identifying patients at low risk of adverse events. Pending further validation, this strategy may reduce the need for serial testing and empirical treatment, enabling earlier reassurance for patients and fewer unnecessary evaluations and hospital admissions.
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J. Am. Coll. Cardiol. · Sep 2011
Comparative StudyActivation and entrainment mapping of hemodynamically unstable ventricular tachycardia using a percutaneous left ventricular assist device.
Our goal was to investigate the effects of percutaneous left ventricular assist device (pLVAD) support during catheter ablation of unstable ventricular tachycardia (VT). ⋯ In patients with scar-related VT undergoing catheter ablation, pLVAD support was able to safely maintain end-organ perfusion despite extended periods of hemodynamically unstable VT. Randomized studies are necessary to determine whether this enhanced ability to perform entrainment and activation mapping will translate into a higher rate of clinical success.
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J. Am. Coll. Cardiol. · Sep 2011
Sudden death in young adults: an autopsy-based series of a population undergoing active surveillance.
The purpose of this study was to define the incidence and characterization of cardiovascular cause of sudden death in the young. ⋯ Prevention of sudden death in the young adult should focus on evaluation for causes known to be associated with SUD (e.g., primary arrhythmia) among persons <35 years of age, with an emphasis on atherosclerotic coronary disease in those ≥ 35 years of age.