Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Jun 2012
Multicenter Study Comparative StudyTranscatheter aortic valve replacement: outcomes of patients with moderate or severe mitral regurgitation.
The aim of this study was to evaluate the impact of mitral regurgitation (MR) on outcomes after transcatheter aortic valve replacement (TAVR) and the impact of TAVR on MR. ⋯ Moderate or severe MR in patients undergoing TAVR is associated with a higher early, but not late, mortality rate. At 1-year follow-up, MR was improved in 55% of patients with moderate or severe MR at baseline. Improvement was more likely in patients with high transaortic gradients, with functional MR, without pulmonary hypertension and without atrial fibrillation.