Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Mar 2000
Multicenter Study Comparative StudyOutcomes of cardiac surgery in patients > or = 80 years: results from the National Cardiovascular Network.
The purpose of this study was to evaluate characteristics and outcomes of patients age > or =80 undergoing cardiac surgery. ⋯ Risks for octogenarians undergoing cardiac surgery are less than previously reported, especially for CABG only or CABG/AVR. In selected octogenarians without significant comorbidity, mortality approaches that seen in younger patients.
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J. Am. Coll. Cardiol. · Mar 2000
Comparative StudyA decrease in diastolic blood pressure combined with an increase in systolic blood pressure is associated with a higher cardiovascular mortality in men.
The study evaluated the risk of cardiovascular mortality according to combined spontaneous (non-treatment-related) changes in both systolic and diastolic blood pressure (BP). ⋯ Assessment of spontaneous changes of BP over a long period of time can contribute to the evaluation of cardiovascular risk. Subjects whose systolic BP increased while their diastolic BP decreased had the highest cardiovascular risk independently of absolute values of BP or other risk factors.
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J. Am. Coll. Cardiol. · Feb 2000
Comparative StudySurvival with full neurologic recovery and no cerebral pathology after prolonged cardiopulmonary resuscitation with vasopressin in pigs.
We sought to determine the effects of vasopressin and saline placebo in comparison with epinephrine on neurologic recovery and possible cerebral pathology in an established porcine model of prolonged cardiopulmonary resuscitation (CPR). ⋯ During prolonged CPR, repeated vasopressin administration, but not epinephrine or saline placebo, ensured long-term survival with full neurologic recovery and no cerebral pathology in this porcine CPR model.
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J. Am. Coll. Cardiol. · Feb 2000
Multicenter Study Comparative Study Clinical TrialSerum amyloid A predicts early mortality in acute coronary syndromes: A TIMI 11A substudy.
We evaluated the ability of serum amyloid A (SAA), alone and in combination with a rapid qualitative assay for cardiac-specific troponin T (cTnT), to predict 14-day mortality in patients with unstable angina or non-Q wave myocardial infarction (NQMI). ⋯ Similar to CRP, baseline elevation of SAA identifies patients hospitalized with unstable angina and NQMI at higher risk for early mortality, even among those with a negative rapid assay for cTnT. These data support further investigation of inflammatory markers used alone and in combination with cardiac troponins for risk assessment in unstable coronary syndromes.