Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Aug 1998
Comparative StudyThree-dimensional echocardiographic planimetry of maximal regurgitant orifice area in myxomatous mitral regurgitation: intraoperative comparison with proximal flow convergence.
We sought to validate direct planimetry of mitral regurgitant orifice area from three-dimensional echocardiographic reconstructions. ⋯ 3D echo imaging of the MV allows direct visualization and planimetry of the ROA in patients with severe MR with good agreement to flow-based proximal convergence measurements.
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J. Am. Coll. Cardiol. · Aug 1998
Comparative StudyFrequency of 22q11 deletions in patients with conotruncal defects.
This study was designed to determine the frequency of 22q11 deletions in a large, prospectively ascertained sample of patients with conotruncal defects and to evaluate the deletion frequency when additional cardiac findings are also considered. ⋯ A substantial proportion of patients with IAA, TA, TOF and PMVSD have a deletion of chromosome 22q11. Deletions are more common in patients with aortic arch or vessel anomalies. These results begin to define guidelines for deletion screening of patients with conotruncal defects.
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J. Am. Coll. Cardiol. · Aug 1998
The effects of ventricular fibrillation duration and site of initiation on the defibrillation threshold during early ventricular fibrillation.
The purpose of this study was to determine if the defibrillation threshold (DFT) is lower during the first few cycles of ventricular fibrillation (VF) than after 10 s of VF and, if so, if the effect is caused by local or global factors. ⋯ This study demonstrates that the DFT is significantly lower during the first few VF cycles of VF than after 10 s of VF and that this decrease may be caused by both local factors and global factors. These results provide an impetus for exploring earlier shock delivery in implantable devices.
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J. Am. Coll. Cardiol. · Aug 1998
Production of oxidative products of nitric oxide in infarcted human heart.
We sought to assess whether oxidation products of nitric oxide (NO), nitrite (NO2-) and nitrate (NO3-), referred to as NOx, are released by the heart of patients after acute myocardial infarction (AMI) and whether NOx can be determined in peripheral blood of these patients. ⋯ The appearance of oxidative products of NO (NO2- and NO3-) in peripheral blood of patients with acute MI is the result of their increased release from infarcted heart during the inflammatory phase of myocardial ischemia. Further studies are needed to define the clinical value of these observations.
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J. Am. Coll. Cardiol. · Aug 1998
Systemic venous collateral development after the bidirectional cavopulmonary anastomosis. Prevalence and predictors.
To determine the prevalence of systemic venous collaterals after the bidirectional cavopulmonary anastomosis and the factors associated with their development. ⋯ Systemic venous collaterals occur frequently after a bidirectional cavopulmonary anastomosis and are found postoperatively when a significant pressure gradient occurs between cava and right atrium.