Resuscitation
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The Federal Islamic Republic of the Comoros lies off between Madagascar and the Southeast Coast of Africa, and comprises a group of three islands with a total population of 651,901. The average annual income per capita is US$ 470 and life expectancies at birth are 59.3 years for men and 63.9 years for women. ⋯ The main focus of emergency medicine is disaster management and hospital-based clinical practice. There is a paucity of literature on emergency medicine in Comoros and this is the first article to report the current status of emergency medicine in Comoros Islands.
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Review
Goal-directed hemodynamic optimization in the post-cardiac arrest syndrome: a systematic review.
The treatment recommendations from the 2005 International Consensus Conference on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science (hosted by the American Heart Association) advocate a goal-directed treatment strategy for hemodynamic optimization after return of spontaneous circulation (ROSC) in post-cardiac arrest care. We performed a systematic review to (1) examine the available evidence for goal-directed hemodynamic support in the post-cardiac arrest syndrome, (2) determine the effect of such a treatment strategy on survival, and (3) define the specific hemodynamic goals, if any, that have been tested in clinical trials of post-cardiac arrest patients. ⋯ To date, no clinical trials have examined hemodynamic optimization in post-cardiac arrest patients. Although clinical acumen may support the concept that hemodynamic derangements after ROSC should be normalized, there is currently no evidence available to indicate the best strategy for goal-directed hemodynamic support. The current study indicates the need for future clinical investigations designed to determine both the efficacy of hemodynamic optimization in post-cardiac arrest patients and the best endpoints to target as part of a goal-directed strategy.
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Although many different drugs and interventions have been studied in cardiac arrest to improve survival rates and neurological outcome, the results are still very poor. Magnesium (Mg) has important electrophysiological effects and normal concentrations are required to maintain regular cardiac conduction, rhythm and vascular tone, but its role in improving survival rates and neurological outcome in victims of cardiac arrest is not completely understood. ⋯ We found that there are very few data available about the role of Mg in the treatment of cardiac arrest. Although two non-randomised and one animal study reported promising results, the lack of high quality studies makes it impossible to recommend for or against the administration of Mg during or early after resuscitation to improve outcome.
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The new resuscitation guidelines permit compressions before delayed, defibrillation, a change that has generally been welcomed. The benefits are generally assumed to relate to the immediate provision of limited coronary perfusion with protection or replenishment of myocardial metabolic reserves. ⋯ We argue that changes in the size and shape of the ventricles are the most important reason for the narrow window of opportunity for defibrillation alone and for the value of compressions in extending this period. We also draw attention to the implication for clinical resuscitation and to one aspect of the current guidelines of the European Resuscitation Council that we believe to be inconsistent with the evidence that we review.
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Good quality basic life support (BLS) improves outcome during cardiac arrest. As fatigue may reduce BLS performance over time we wanted to examine the quality of chest compressions in a single-rescuer scenario during prolonged BLS with different compression:ventilation ratios (C:V ratios). ⋯ Increasing the C:V ratio increases the number of chest compressions during 10 min of BLS. Compression depth and compression rate were within guideline recommendations for all three ratios. We found no decline in chest compression quality below guideline recommendations during 10 min of BLS with any of the three different C:V ratios.