Resuscitation
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To determine if the quality of CPR had a significant interaction with the primary study intervention in the NIH PRIMED trial. ⋯ There was a statistically significant interaction between the quality of CPR provided, intervention, and survival to hospital discharge with mRS ≤ 3 in the NIH PRIMED trial. Quality of CPR delivered can be an underestimated effect modifier in CPR clinical trials.
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Multicenter Study
Out-of-hospital cardiac arrest in the elderly: A large-scale population-based study.
There is little information on elderly people who suffer from out-of-hospital cardiac arrest (OHCA). ⋯ Advanced age is an independent predictor of mortality in OHCA patients over 70 years of age. However, even in patients above 90 years of age, defined subsets with a survival rate of more than 10% exist. In survivors, the neurological outcome remains similar regardless of age.
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Multicenter Study Observational Study
Time on the scene and interventions are associated with improved survival in pediatric out-of-hospital cardiac arrest.
Survival is less than 10% for pediatric patients following out-of-hospital cardiac arrest. It is not known if more time on the scene of the cardiac arrest and advanced life support interventions by emergency services personnel are associated with improved survival. ⋯ In this observational study, a scene time of 10 to 35 min was associated with the highest survival, especially among adolescents. Access for fluid resuscitation was associated with increased survival but advanced airway and resuscitation drugs were not.