European journal of anaesthesiology
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Randomized Controlled Trial Comparative Study
Comparison of the antiemetic effect of ramosetron and combined ramosetron and midazolam in children: a double-blind, randomised clinical trial.
Postoperative nausea and vomiting remains a clinically important problem after strabismus surgery in children. ⋯ Adding midazolam to ramosetron had no advantages over ramosetron alone in reducing the incidence of postoperative nausea and vomiting in children undergoing strabismus surgery.
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Airway management of patients with dental cellulitis can be difficult due to laryngeal deviation and oedema. Awake fibre-optic intubation has been recommended. ⋯ Most patients with dental cellulitis can be safely intubated through direct laryngoscopy even if mouth opening is limited.
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Randomized Controlled Trial Meta Analysis Comparative Study
Remifentanil for labour analgesia: a meta-analysis of randomised controlled trials.
Remifentanil is a potent short-acting μ-opioid receptor agonist which is rapidly metabolised in the mother and fetus and may be ideal for labour analgesia. ⋯ During labour, remifentanil-PCA provided superior analgesia and higher patient satisfaction compared with pethidine with a comparable degree of adverse events. Epidural analgesia provided superior pain relief in comparison with remifentanil. Due to a low number of reported adverse events, the safety issue of remifentanil use in labour remains an open question that needs to be addressed in future trials.