European journal of anaesthesiology
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Comparative Study
Differential protective effects of anaesthesia with sevoflurane or isoflurane: An animal experimental model simulating liver transplantation.
The mechanisms involved in organ protection by volatile anaesthetics are not completely understood. In the liver transplant setting, there is a lack of information in the literature about whether sevoflurane anaesthesia has a superior hepatoprotective effect when compared with isoflurane. ⋯ These results suggest that sevoflurane anaesthesia seems to have superior protective and antioxidant effects to isoflurane anaesthesia, not only during cold preservation but also in the early phase of liver reperfusion.