European journal of anaesthesiology
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Meta Analysis
Pre-operative proteinuria, postoperative acute kidney injury and mortality: A systematic review and meta-analysis.
To investigate the association of pre-operative proteinuria with postoperative acute kidney injury (AKI) development as well as the requirement for a renal replacement therapy (RRT) and mortality at short-term and long-term follow-up. ⋯ CRD42020190065.
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Randomized Controlled Trial Observational Study
Magnetic resonance imaging of cerebrospinal fluid spread in the epidural space correlates with the severity of postdural puncture headache in obstetric patients: A proof-of-concept study.
Currently, performing an epidural blood patch (EBP) for postdural puncture headache (PDPH) remains a subjective clinical decision. An evidence-based protocol may be of value in identifying women at high risk of developing a severe PDPH. ⋯ ISRCTN14959004, https://www.isrctn.com/.
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Ryanodine receptor type 1 (RYR1) sequence variants are pathogenic for malignant hyperthermia. Variant carriers have a subtle increase in resting myoplasmic calcium concentration compared with nonaffected individuals, but whether this has metabolic effects in daily life is unknown. ⋯ The observed tendency towards lower BMI values in carriers of malignant hyperthermia-pathogenic RYR1 sequence variants points to a possible protective effect on obesity. This study confirms regional differences of the prevalence of malignant hyperthermia-pathogenic RYR1 sequence variants, with just three variants covering 75% of Swiss MHS families.
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Meta Analysis
Transversus abdominis plane block in urological procedures: A systematic review and meta-analysis.
Transversus abdominis plane (TAP) blocks have been shown to successfully reduce pain and opioid consumption after general and gynaecological surgery. ⋯ PROSPERO CRD42018112737.