Anaesthesia and intensive care
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Anaesth Intensive Care · Jan 2010
Comparative StudyComparison of the Pentax Airway Scope and McGrath Videolaryngoscope with the Macintosh laryngoscope in tracheal intubation by anaesthetists unfamiliar with videolaryngoscopes: a manikin study.
Videolaryngoscopes are becoming widely available and have been suggested as a replacement for the Macintosh in cases of cervical instability or even for use in the first instance. There is limited existing data on the use of videoscopes by experienced anaesthetists who are inexperienced in the use of videoscopes. We used a manikin model to compare time to intubation between the Macintosh blade, Pentax Airway Scope and the McGrath videolaryngoscope in a simulated urgent intubation by 23 experienced anaesthetists with no prior experience in the use of these videoscopes. ⋯ Only 48% of participants (n=11) could intubate within three minutes using the McGrath videolaryngoscope and required a median of three attempts. This difference occurred despite the majority of anaesthetists obtaining a Grade 1 Cormack and Lehane view with both videoscopes. We demonstrated that anaesthetists who were naive to these videoscopes can successfully intubate the trachea using the Pentax Airway Scope but not the McGrath videolaryngoscope.
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Anaesth Intensive Care · Jan 2010
Clinical TrialMagnesium sulphate for treatment of tetanus in adults.
There are reports that suggest that magnesium sulphate alone may control muscle spasms thereby avoiding sedation and mechanical ventilation in tetanus, but this has not been confirmed. We examined the efficacy and safety of intravenous magnesium sulphate for control of rigidity and spasms in adults with tetanus. A prospective clinical study of intravenous magnesium sulphate was carried out over a period of two years in a tertiary care teaching hospital. ⋯ The average duration of ventilatory support was 18.3 +/- 16.0 days and the overall mortality was 22.9%. Asymptomatic hypocalcaemia was a universal finding. Magnesium sulphate therapy alone may not be efficacious for the treatment of severe tetanus.
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Anaesth Intensive Care · Jan 2010
Ocular surface bacterial colonisation in sedated intensive care unit patients.
We investigated the time-dependent ocular surface bacterial colonisation of sedated patients hospitalised in an intensive care unit and aimed to evaluate whether proper topical antibiotic prophylaxis could prohibit corneal infection. The study lasted 12 months and included 134 patients undergoing sedation and mechanical respiratory support for various medical reasons. Patients hospitalised for less than seven days and those with pre-existing ocular surface pathology were excluded. ⋯ Infectious keratitis was prohibited in all cases. Ocular surface of long-term sedated patients was found to be colonised by various bacterial species and their isolation was closely associated with the time period of hospitalisation. The results of this study suggest that the early identification of ocular surface bacteria colonisation and the administration of topical antibiotics for prophylaxis can prohibit corneal infection in these patients.
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Anaesth Intensive Care · Jan 2010
The effect of dexmedetomidine on agitation during weaning of mechanical ventilation in critically ill patients.
Ventilated patients receiving opioids and/or benzodiazepines are at high risk of developing agitation, particularly upon weaning towards extubation. This is often associated with an increased intubation time and length of stay in the intensive care unit and may cause long-term morbidity. Anxiety, fear and agitation are amongst the most common non-pulmonary causes of failure to liberate from mechanical ventilation. ⋯ Excluding unrelated clinical deterioration, 22 episodes (73.3%) achieved successful weaning from ventilation with a median (interquartile range) ventilation time of 70 (28 to 96) hours after dexmedetomidine infusion. Dexmedetomidine achieved rapid resolution of agitation and facilitated ventilatory weaning after failure of conventional therapy. Its role as first-line therapy in ventilated, agitated patients warrants further investigation.