Anaesthesia and intensive care
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Anaesth Intensive Care · Jan 2012
Plasma free cortisol and B-type natriuretic peptide in septic shock.
Previous studies of patients with septic shock have independently demonstrated alterations in plasma concentrations of B-type natriuretic peptide and plasma free cortisol. Previous data suggest that a reciprocal relationship might exist. However, the relationship between these hormones in patients with septic shock is unclear. ⋯ A model incorporating both variables explained 68% of variation in plasma free cortisol (R-square=0.682). This study of patients with septic shock demonstrates a previously unappreciated positive correlation between plasma free cortisol and b-type natriuretic peptide concentration. Acute Physiology and Chronic Health Evaluation III score and noradrenaline dose were independent predictors of plasma free cortisol.
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Anaesth Intensive Care · Jan 2012
Editorial CommentRisks of anaesthesia and surgery in elderly patients.