Anaesthesia and intensive care
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Anaesth Intensive Care · Nov 1981
ReviewFactors affecting an anaesthetist's work: some findings on vigilance and performance.
This paper reviews factors which may influence the vigilance tasks of an anaesthetist during an anaesthetic. Vigilance tasks are found to be unlike any other automatic, repetitive or monotonous tasks. ⋯ We suggest, however, that there are many parallels between findings related to vigilance in general and the type of work done by anaesthetists. Implications of major factors are discussed, and recommendations for further study are proposed.
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The autonomic nervous system may play an important role in tissue autoregulation as the neurohumoral transmission process has been shown to constitute the final common pathway by which the effects of many physiological and pharmacological substances are mediated. The effects of the administration of a sympathomimetic amine cannot be accurately predicted in a subject. ⋯ It is the drug of first choice in anaphylactic reactions and for severe allergic bronchospasm, and is widely used as a vasoconstrictor in surgery and with local anaesthetic agents. Adrenaline in "physiological" doses is a satisfactory and cheap alternative to other available drugs for use in septic shock and in emergence from cardiopulmonary bypass.
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Anaesth Intensive Care · Aug 1975
Review Case ReportsSevere histamine mediated reactions to intravenous drugs used in anaesthesia.
Severe histamine mediated reactions to intravenous drugs used in anaesthesia may occur as a result of anaphylactic and anaphylactoid reactions. The incidence is rare, but appears to be increasing. ⋯ Six cases of severe histamine mediated reactions are presented and detailed analyses of the drugs in these and other reported reactions is made showing varied clinical patterns with different drugs. The prevention, treatment, and follow-up of severe histamine mediated reactions are considered.