Anaesthesia and intensive care
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Anaesth Intensive Care · Aug 2007
Randomized Controlled Trial Comparative StudyComparative safety and efficacy of two high dose regimens of oral paracetamol in healthy adults undergoing third molar surgery under local anaesthesia.
This study compared the efficacy and safety of single oral doses of 60 mg/kg and 90 mg/kg paracetamol in fit young adult patients undergoing third molar extractions. The study was a randomised, blinded, crossover design on 20 young, fit adults. ⋯ There was a reduction in factor VII activity with 90 mg/kg dose compared to 60 mg/kg dose. It may be concluded that the 90 mg/kg dose, though safe, does not offer any advantages over 60 mg/kg dose of paracetamol in young fit adults undergoing third molar surgery.
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Anaesth Intensive Care · Aug 2007
Multicenter StudyAirway management equipment in a metropolitan region: an audit.
Difficult airway equipment containers are commonly found in operating rooms, but the availability of airway equipment beyond that environment is unknown. Using the Difficult Airway Society (U. K.) and American Society of Anesthesiologists' guidelines, we conducted an inspection audit of airway equipment at all anaesthetic sites in our region. ⋯ One third of the items with an expiry date were expired. Quality control and implementation of airway guidelines could rectify these deficiencies. Anaesthesia organisations should be encouraged to publish detailed equipment guidelines.
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Anaesth Intensive Care · Aug 2007
Case ReportsSildenafil may facilitate weaning in mechanically ventilated COPD patients: a report of three cases.
We report three cases of mechanically ventilated chronic obstructive pulmonary disease patients who were intubated due to an exacerbation of their disease and who presented with repeated spontaneous breathing trial failures. Patients were given 50 mg of sildenafil through the nasogastric tube, under close monitoring of haemodynamic and ventilatory parameters. ⋯ Cardiac output increased in two of the patients, while all of them were successfully extubated. This is the first report of successful extubation after sildenafil use.