Anaesthesia and intensive care
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Anaesth Intensive Care · Aug 1983
Case ReportsAnaesthetic implications of the mucopolysaccharidoses: a fifteen-year experience in a children's hospital.
Patients suffering from the mucopolysaccharidoses, most commonly Hurler's syndrome, present special problems in anaesthesia. A retrospective review of the anaesthetic management of such patients over fifteen years revealed a high incidence of airway problems. Two case histories illustrating these difficulties are presented.
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Morphine sulphate 5 mg and placebo administered epidurally after caesarean section under epidural analgesia were compared in a double-blind fashion. Morphine was significantly superior to placebo for pain relief, duration of pain relief, and reduction of parenteral narcotic requirements. ⋯ There was no statistical difference between morphine and placebo in the incidence of urinary catheterisation, vomiting, nausea, dizziness or drowsiness. No serious respiratory depression requiring treatment was observed.
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Anaesth Intensive Care · May 1983
Comparative StudyA comparison of methods of cardiac output measurement.
Cardiac output measurements determined by dye dilution, iced-injectate thermodilution and room temperature thermodilution were compared in man in order to assess the random error of each method and to examine the systematic error of both thermodilution methods in comparison with dye dilution. Results showed that random error was greatest with room temperature thermodilution and least using iced thermodilution. Iced thermodilution correlated well with dye dilution, tending to overestimate cardiac output only at low flows. Room temperature thermodilution, however, overestimated cardiac output by up to 25% in the clinically important range and more so at low cardiac output.