The Clinical journal of pain
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To provide a descriptive account of long-term functioning (≥5 y posttreatment) among youth who completed intensive interdisciplinary pain treatment (IIPT) for pediatric chronic pain conditions. ⋯ Results show long-term positive functioning among individuals who underwent intensive rehabilitation treatment for chronic pain as children or adolescents. Despite experiencing one or more pain flares at some point after treatment, most former IIPT patients report minimal to no ongoing functional disability, complete or partial resolution of pain symptoms, and developmentally appropriate progress toward goals (eg, school completion, independent living).
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It has been reported that the optimal concentration of epidural dexmedetomidine for labor analgesia is 0.5 μg/mL when combined with 0.1% ropivacaine. This study investigated the median effective concentration (EC50) of epidural ropivacaine for labor analgesia when combined with 0.5 μg/mL dexmedetomidine. ⋯ The EC50 of epidural ropivacaine for labor analgesia was 0.083% (95% CI, 0.077%-0.089%) and decreased to 0.062% (95% CI, 0.058%-0.066%) when combined with 0.5 μg/mL dexmedetomidine (http://www.chictr.org.cn, registration number: ChiCTR-OPC-16008548).
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Observational Study
Unilateral Lateral Epicondylalgia Shows a Pro-nociceptive Pain Profile: A Case-control Observational Study.
Lateral epicondylalgia (LE, tennis elbow) is characterized by both local tissue pathology and features indicative of secondary hyperalgesia. The aim of this study was to evaluate endogenous pain modulation characteristics in people with chronic LE, and to investigate the relationship between endogenous pain modulation and clinical characteristics. ⋯ LE is characterized by locally increased facilitation of pain, as measured by TS, but this is not associated with severity of pain or disability.