The Clinical journal of pain
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Randomized Controlled Trial
Evaluation of the analgesic efficacy of local dexmedetomidine application.
To determine the analgesic effects of locally applied dexmedetomidine in third molar surgery under general anesthesia. ⋯ Dexmedetomidine seems to have an antihyperalgesic effect when administered locally after bilateral third molar surgery. There is no delay in psychomotor recovery or increase in postoperative clinically significant adverse events.
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Randomized Controlled Trial
Effectiveness of leech therapy in chronic lateral epicondylitis: a randomized controlled trial.
Leech therapy has been found to be effective in osteoarthritis of the knee and hand in previous trials. Chronic epicondylitis is a prevalent pain syndrome with limited treatment options. In this study, we tested whether leech therapy would be beneficial in the symptomatic treatment of chronic lateral epicondylitis. ⋯ A single course of leech therapy was effective in relieving pain in the short-term and improved disability in intermediate-term. Leeches might be considered as an additional option in the therapeutic approach to lateral epicondylitis.
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Our primary goals were to determine whether preexisting fear of pain and pain sensitivity contributed to post-exercise pain intensity. ⋯ Combined, these findings suggest that the initial reports of pain after injury may be more strongly influenced by fear whereas the inflammatory process and pain sensitivity may play a larger role for later pain intensity reports.
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To investigate the effect of experimental neck muscle pain on the activation of the cervical extensor muscles during the performance of a cervical extension exercise by the use of muscle functional magnetic resonance imaging. ⋯ This is the first study that has shown pain to immediately affect the activity of both deep and superficial cervical extensor muscle layers during a cervical extension exercise. The findings support recommendations for evaluation of cervical extensor muscle function early in the management of painful cervical spine injuries.
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Randomized Controlled Trial Multicenter Study Clinical Trial
Treatment expectation for pain coping skills training: relationship to osteoarthritis patients' baseline psychosocial characteristics.
This study examined predictors of treatment expectation among osteoarthritis (OA) patients in a multisite clinical trial of pain coping skills training (CST). ⋯ Although many OA patients will approach pain CST with positive expectations, others have lower expectations. This study suggests that a multidimensional assessment of OA patients with chronic pain can identify those who have higher expectations versus lower expectations. The results suggest that patients who are psychologically distressed are less optimistic about engaging in treatment and that these patients, in particular, may benefit from and need pretreatment motivational interviewing to enhance their uptake of pain coping skills.