The Clinical journal of pain
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Randomized Controlled Trial
Short-Term Effects of a Manual Therapy Protocol on Pain, Physical Function, Quality of Sleep, Depressive symptoms and Pressure Sensitivity in Women and Men with Fibromyalgia Syndrome: A Randomized Controlled Trial.
To investigate the therapeutic effects of a manual therapy protocol for improving pain, function, pressure pain thresholds (PPT), quality of sleep, and depressive symptoms in women and men with fibromyalgia syndrome (FMS). ⋯ Manual therapy protocol was effective for improving pain intensity, widespread pressure pain sensitivity, impact of FMS symptoms, sleep quality, and depressive symptoms. In addition, sex differences were observed in response to treatment: women and men get similar improvements in quality of sleep and tender point count, whereas women showed a greater reduction in pain and impact of FMS symptoms than men, but men reported higher decreases in depressive symptoms and pressure hypersensitivity than women.
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Randomized Controlled Trial Multicenter Study
Co-bedding Between Preterm Twins Attenuates Stress Response Following Heel Lance: Results of a Randomized Trial.
To examine the effect of co-bedding between preterm twins on stress response after heel lance. ⋯ Co-bedding attenuates the stress response of preterm twins undergoing heel lance.
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Randomized Controlled Trial
Efficacy of Postoperative Continuous Wound Infiltration With Local Anesthesia After Open Hepatectomy.
Local anesthetic wound infiltration is widely used as an effective adjunct during multimodal postoperative pain management. The aim of this study was to evaluate the effectiveness of continuous wound infusion of ropivacaine in postoperative pain relief, opioid sparing, incidence of nausea and vomiting, and bowel and liver function improvement in patients undergoing open hepatectomy. ⋯ Surgical wound infusion with ropivacaine after hepatectomy can improve pain relief at rest and accelerate recovery and discharge.
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Randomized Controlled Trial Comparative Study
The Subjective Psychoactive Effects of Oral Dronabinol Studied in a Randomized, Controlled Crossover Clinical Trial For Pain.
The oral cannabinoid dronabinol has similar psychoactive effects to smoking marijuana.
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Randomized Controlled Trial
Perioperative Epidural or Intravenous Ketamine Does Not Improve the Effectiveness of Thoracic Epidural Analgesia for Acute and Chronic Pain After Thoracotomy.
Persistent postsurgical pain (PPP) after thoracotomy effect 50% to 80%. Nerve damage and central sensitization involving NDMDAr activation may play an important role. This study evaluates the efficacy of adding intravenous (IV) or epidural ketamine to thoracic epidural analgesia (TEA) after thoracotomy. ⋯ Adding epidural or IV racemic ketamine to TEA after thoracotomy did not lead to any reduction in PPP or allodynia. Epidural administration produced similar plasma ketamine levels to the IV route.