The Clinical journal of pain
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Randomized Controlled Trial
Effect of targeted strength, endurance, and coordination exercise on neck and shoulder pain among fighter pilots: a randomized-controlled trial.
To explore in Danish F-16 pilots: (1) the effect on neck and shoulder pain of a 24-week training intervention including targeted training of the deep neck muscles; (2) selected clinical signs and symptoms at baseline; (3) the prevalence and intensity of neck and shoulder pain. ⋯ High prevalences of self-reported neck and shoulder pain and clinical signs and symptoms were found among Gz-exposed F-16 pilots with repeated whiplash-like exposures. Twenty-four weeks of targeted training combining deep neck muscle, strength, and endurance training proved effective in reducing neck pain.
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Randomized Controlled Trial
A randomized-controlled trial of using a book of metaphors to reconceptualize pain and decrease catastrophizing in people with chronic pain.
Reconceptualization of pain and reduction of pain-related catastrophizing are primary objectives in chronic pain rehabilitation. Teaching people about the underlying biology of pain has been shown to facilitate these objectives. The objective of this study was to investigate whether written metaphor and story can be used to increase knowledge of the biology of pain and reduce pain-related catastrophizing. ⋯ We conclude that providing educational material through metaphor and story can assist patients to reconceptualize pain and reduce catastrophizing. Metaphor and story could be used as a precurser to other interventions that target functional capacity.
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Randomized Controlled Trial Multicenter Study
The effects of low doses of pregabalin on morphine analgesia in advanced cancer patients.
The aim of this study was to evaluate the opioid response in patients receiving morphine and pregabalin, independently from the presumed pain mechanisms, in comparison with patients receiving morphine treatment only. ⋯ The use of low doses of pregabalin added to morphine therapy in advanced cancer patients does not seem to provide advantageous analgesic effects, despite limitations of the present study due to the number of drop-outs.
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Randomized Controlled Trial
Acid sensitization of esophageal mucosal afferents: implication for symptom perception in patients across the gastroesophageal reflux disease spectrum.
Sensitization of esophageal chemoreceptors, either directly by intermittent acid exposure or indirectly through esophagitis-associated inflammatory mediators, is likely to be the mechanism underlying the perception of heartburn. ⋯ (1) Esophageal acid infusion sensitizes it to subsequent electrical and chemical stimulation. (2) The acid-related sensitization is greater in gastroesophageal reflux disease than in controls and may influence in part symptom perception in this population. (3) Acid-related sensitization within the gastroesophageal reflux disease population is not dependant on mucosal inflammation.
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Randomized Controlled Trial
Parent satisfaction with acute pediatric pain treatment at home.
Outpatient pain management after acute injuries is an important part of emergency department (ED) care, but there is little evidence to support best practice. Satisfaction with care is one way to assess the effectiveness of current practice. This study describes the outpatient pain experience for children with an arm fracture and explores the variables associated with parents' dissatisfaction with pain treatment for 2 analgesics after ED care. ⋯ Children with arm fractures experience noteworthy pain in the outpatient setting. Parents' dissatisfaction with home pain management for children suggests that more research is needed to evaluate the factors that result in improvements in both parent and child satisfaction and the most effective way of producing those changes.