The Clinical journal of pain
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Randomized Controlled Trial
Preoperative cotreatment with dextromethorphan and ketorolac provides an enhancement of pain relief after laparoscopic-assisted vaginal hysterectomy.
Both N-methyl-D-aspartate receptor antagonists and nonsteroidal anti-inflammatory drugs have been demonstrated to produce better postoperative pain relief. The concept of multimodal analgesia has also been used for clinical pain management. The aim of the present study was to examine the analgesic effect of preoperative cotreatment with dextromethorphan (DM) and ketorolac on postoperative pain management after laparoscopic-assisted vaginal hysterectomy (LAVH). ⋯ Preoperative treatment with both DM and ketorolac diminish postoperative pain. Our results suggest that the N-methyl-D-aspartate antagonist-DM and the nonsteroidal anti-inflammatory drugs-ketorolac cotreatment provide an enhancement of analgesia for postoperative pain management in patients after LAVH surgery.
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Randomized Controlled Trial
Efficacy of transcutaneous electrical nerve stimulation (tens) for chronic low-back pain in a multiple sclerosis population: a randomized, placebo-controlled clinical trial.
This study was designed to investigate the hypoalgesic effects of self-applied transcutaneous electrical nerve stimulation (TENS) on chronic low-back pain (LBP) in a multiple sclerosis (MS) population. ⋯ Although not statistically significant, the observed effects may have implications for the clinical prescription and the use of TENS within this population.
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Randomized Controlled Trial
Sensitivity to change and internal consistency of the Northwick Park Neck Pain Questionnaire and derivation of a minimal clinically important difference.
To estimate the sensitivity to change and internal consistency of the Northwick Park Neck Pain Questionnaire (NPQ) and derive its minimal clinically important difference (MCID). ⋯ These results show high internal consistency and sensitivity to change for the NPQ, and provide an MCID that allows participants with varying levels of severity to demonstrate improvement.
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Randomized Controlled Trial Comparative Study Clinical Trial
Early access to physical therapy treatment for subacute low back pain in primary health care: a prospective randomized clinical trial.
To evaluate the effects of early access (EA) to physical therapy treatment for patients with subacute low back pain compared to access with a 4-week waiting list. ⋯ This study indicated that EA to physical therapy resulted in greater improvement in perceived pain at 6 months compared to later access. In this study, EA to physical therapy could be introduced by reorganization without additional resources.
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Randomized Controlled Trial Comparative Study Clinical Trial
Topiramate in treatment of patients with chronic low back pain: a randomized, double-blind, placebo-controlled study.
Chronic low back pain (CLBP) is a widespread ailment. The aim of this study was to assess the efficacy of topiramate in the treatment of CLBP and the changes in anger status and processing, body weight, subjective pain-related disability and health-related quality of life during the course of treatment. ⋯ Topiramate seems to be a relatively safe and effective agent in the treatment of CLBP. Significantly positive changes in pain sensitivity, anger status and processing, subjective disability, health-related quality of life, and loss of weight were observed.