Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
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Otolaryngol Head Neck Surg · Feb 2005
Randomized Controlled Trial Comparative Study Clinical TrialRandomized controlled trial of Coblation versus electrocautery tonsillectomy.
To compare the postoperative recovery of patients receiving Coblation-assisted (Arthrocare, Sunnyvale, CA) intracapsular tonsillectomy with that of patients receiving traditional subcapsular electrocautery tonsillectomy. ⋯ Children with obstructive sleep apnea undergoing tonsillectomy and adenoidectomy demonstrate significantly better postoperative recovery after Coblation-assisted intracapsular tonsillectomy.
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Otolaryngol Head Neck Surg · Feb 2005
Randomized Controlled Trial Comparative Study Clinical TrialCelecoxib and ketoprofen for pain management during tonsillectomy: a placebo-controlled clinical trial.
To evaluate the efficacy and safety of celecoxib and ketoprofen in pain management during tonsillectomy in 120 patients. ⋯ Celecoxib seems to be more effective and safe than ketoprofen for pain management after discharge in patients with tonsillectomy.
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Otolaryngol Head Neck Surg · Nov 2004
Randomized Controlled Trial Comparative Study Clinical TrialProspective, randomized, controlled clinical trial of a novel matrix hemostatic sealant in children undergoing adenoidectomy.
Floseal is a novel matrix hemostatic sealant composed of collagen-derived particles and topical bovine-derived thrombin. It is applied as a high-viscosity gel for hemostasis and has been clinically proven to control bleeding. This study is a prospective, randomized, controlled clinical trial of Floseal sealant compared to traditional suction cautery hemostasis in children undergoing adenoidectomy. ⋯ Floseal matrix hemostatic sealant is a safe, efficacious, easy, and cost-effective technique for obtaining hemostasis in children undergoing adenoidectomy. Limitations of the study include the fact that it is nonblinded, which does allow for some bias in the subjective data recorded. However, utilizing 4 different operating surgeons, 3 of whom were not affiliated with the study, minimized this. CLINICAL SIGNIFICANCE OF STUDY: This study demonstrates the safety and efficacy of a novel hemostatic sealant in children undergoing adenoidectomy. Floseal matrix hemostatic sealant can be used as a first-line hemostatic agent, and it is a good tool in the armamentarium of otolaryngologists who encounter significant bleeding following adenoidectomy.
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Otolaryngol Head Neck Surg · Nov 2004
Randomized Controlled Trial Comparative Study Clinical TrialEffects of buffered saline solution on nasal mucociliary clearance and nasal airway patency.
To compare the effects of buffered hypertonic and buffered normal saline nasal spray on mucociliary clearance and nasal airway patency. ⋯ B-2.
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Otolaryngol Head Neck Surg · Nov 2004
Randomized Controlled Trial Clinical TrialOral dextromethorphan reduces perioperative analgesic administration in children undergoing tympanomastoid surgery.
To determine whether oral dextromethorphan (1 mg/kg) given one hour prior to surgery decreases opioid administration in the perioperative period in children undergoing tympanomastoid surgery. ⋯ A.