Diabetes research and clinical practice
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Diabetes Res. Clin. Pract. · Nov 2020
Clinical TrialFasting blood glucose level is a predictor of mortality in patients with COVID-19 independent of diabetes history.
No study elucidated the role of fasting blood glucose (FBG) level in the prognosis of coronavirus disease 2019 (COVID-19). ⋯ We firstly showed FBG ≥7.0 mmol/L predicted worse outcome in hospitalized patients with COVID-19 independent of diabetes history. Our findings indicated screening FBG level is an effective method to evaluate the prognosis of patients with COVID-19.
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Diabetes Res. Clin. Pract. · Nov 2020
Correlation of serum meteorin-like concentrations with diabetic nephropathy.
Meteorin-like (Metrnl), a secreted myokine, is induced in white adipose tissue during cold exposure and in muscle after exercise. The present investigation aims to determine the hypothesis that serum Metrnl concentrations are correlated with diabetic nephropathy (DN). ⋯ Serum Metrnl concentrations are inversely correlated with renal function and DN.
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Diabetes Res. Clin. Pract. · Oct 2020
Identifying the quantity and assessing the quality of clinical practice guidelines for the treatment and management of type 2 diabetes: A systematic review.
Type 2 diabetes (T2D) is a condition where the body becomes insulin resistant and cannot use insulin made by the pancreas or is relatively insulin deficient causing high blood glucose levels. Assessing the quality of clinical practice guidelines (CPGs) for T2D is important to identify knowledge gaps and where improvements can be made. The purpose of this review was to identify the quantity and assess the quality of CPGs for the treatment and/or management of T2D. ⋯ CPGs that achieved higher AGREE II scores and favourable overall recommendations could be used by healthcare providers to facilitate informed discussions surrounding T2D therapies. CPGs that received lower scaled domain percentages or overall recommendations could be improved by using the AGREE II instrument.
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Diabetes Res. Clin. Pract. · Sep 2020
Hyperglycemia is a strong predictor of poor prognosis in COVID-19.
The objective of this study is to explore the association between documented diabetes, fasting plasma glucose (FPG), and the clinical outcomes of Coronavirus disease 2019 (COVID-19). ⋯ Hyperglycemia and a history of diabetes on admission predicted poor clinical outcomes in COVID-19.
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Diabetes Res. Clin. Pract. · Sep 2020
Testing for gestational diabetes during the COVID-19 pandemic. An evaluation of proposed protocols for the United Kingdom, Canada and Australia.
We assessed how altered diagnostic processes and criteria for gestational diabetes mellitus (GDM) recommended by the United Kingdom (UK), Canada and Australia for use during the COVID-19 pandemic would affect both GDM frequency and related adverse outcomes. ⋯ The modifications in GDM diagnosis proposed for the UK, Canada and Australia result in differing reductions of GDM frequency. Each has both potential benefits in terms of reduction in potential exposure to COVID-19 and costs in terms of missed opportunities to influence pregnancy and postpartum outcomes. These factors should be considered when deciding which protocol is most appropriate for a particular context.