The Laryngoscope
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The aim of this article is to study the clinical features, management, and outcome in adult patients with acute supraglottitis. ⋯ Acute supraglottitis in adults seems to be a different entity than epiglottitis in children, and inflammation does not usually exclusively involve the epiglottis. Early diagnosis seems to decrease the need for airway intervention and to permit the successful treatment of the patient with intravenous antibiotics and corticosteroids. Streptococcus appears as the dominant causative microorganism. However systemic diseases and other local infections that compromise the regional supraglottic immunity may increase the risk for acute supraglottitis.
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Incoming otolaryngology residents are expected to triage and manage airway, bleeding, and other emergencies with little prior experience. Simulation-based education has become increasingly important as it provides tools to develop psychomotor skills and judgment early in residency, using realistic experiences while eliminating patient risk. We hypothesize that a Boot Camp course emphasizing basic otolaryngology management will increase participants' confidence and be perceived as useful in developing their knowledge, technical skills, self-confidence, and improving clinical performance, both immediately and 6 months following the course. ⋯ An intensive, simulation-based Boot Camp addressing airway, bleeding, and other otolaryngology emergencies was successful in improving junior otolaryngology residents' confidence and was perceived as useful in developing knowledge, technical skills, self-confidence, and improving clinical performance.
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To determine if recombinant human bone morphogenetic protein-2 (rhBMP-2) has biological effects on the invasiveness of human oral squamous cell carcinoma (OSCCA) cell lines. ⋯ Recombinant human BMP-2 has an adverse biological effect on invasiveness of human OSCCA cell lines in vitro. This adverse effect is dependent on the baseline gene expression of BMP-2. Changes in expression of genes involved with tumor metastasis correlated to the invasion assay findings. These data raise concern for the safe application of rhBMP-2 for reconstruction of bone defects in oral cancer patients.
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To describe our technique and initial experience of intraoperative tumor localization with surgeon-performed ultrasound-guided needle dye injection. ⋯ At the conclusion of this manuscript, the participants should be able to understand the technique and advantages of intraoperative tumor localization with surgeon-performed ultrasound-guided needle blue dye injection.