Current medical research and opinion
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Prognostic value of pretreatment immune inflammation indices in patients with immune-related tumors.
Pretreatment high levels of lactate dehydrogenase (LDH), neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), monocyte-lymphocyte ratio (MLR), modified Glasgow prognostic scores (mGPS), prognostic nutritional index (PNI), and other prognostic biomarkers have been associated with poor overall survival (OS) in immune-related tumor types. Therefore, we explored a simple, inexpensive and effective method for cancer prognosis. ⋯ In our cohort, elevated pre-treatment MLR, LDH and ECOG ≥2 were associated with poor OS and PFS. Prospective studies need to determine the utility of them.
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Although diversity, equity, and inclusion (DEI) initiatives are progressively being implemented across various arenas in academic medicine, biomedical research, and healthcare, significant inequities throughout medicine and biomedical research remain. One means by which to rectify these long-standing inequities is through the implementation of a position dedicated to DEI among journal editorial boards; thus, we sought to assess the extent to which this position has been implemented among high-impact biomedical research journals. ⋯ Few of the most influential biomedical journals have implemented a formal, named position dedicated to DEI. Biomedical journals should consider establishing a dedicated DEI editorial position, and ensure this individual position is publicly denoted on the editorial board.