Journal of critical care
-
Journal of critical care · Dec 2012
ReviewUncommon ophthalmologic disorders in intensive care unit patients.
Ophthalmologic complications are frequently encountered in intensive care unit (ICU) patients (Grixti et al. Ocul Surf 2012;10(1):26-42). However, eye care is often overlooked in the critical care setting or just limited to the ocular surface because treatment is focussed on the management of organ failures. ⋯ The most prevalent ophthalmologic disorders identified in critically ill subjects include exposure keratopathy, chemosis, and microbial keratitis. In addition, uncommon eye disorders reported in ICU include metastatic endogenous endophthalmitis, acute primary angle closure, ischemic optic neuropathy, pupil abnormalities, vascular occlusions, and rhino-orbital cerebral mucormycosis. Early diagnosis and effective treatment will help to prevent visual loss.
-
Journal of critical care · Dec 2012
Use of 2-hour creatinine clearance to guide cessation of continuous renal replacement therapy.
A simple test that could guide successful cessation of continuous renal replacement therapy (CRRT) in critically ill patients would be clinically useful. This study aimed to investigate whether a 2-hour creatinine clearance (2h-CrCl) measurement could more accurately predict successful cessation of CRRT than serum creatinine or urine output alone. ⋯ 2h-CrCl may be a useful measurement to help guide discontinuation from CRRT.
-
Journal of critical care · Dec 2012
Beneficial role of endogenous immunoglobulin subclasses and isotypes in septic shock.
There is increasing evidence on the relationship between endogenously produced immunoglobulins and the clinical outcome in septic shock (SS). ⋯ Our study evidenced that, in addition to IgG1, other major endogenous immunoglobulins isotypes and subclasses seem to play a beneficial role in SS.
-
Journal of critical care · Dec 2012
Response to a bolus of conivaptan in patients with acute hyponatremia after brain injury.
The aim of the study was to analyze the response to the vasopressin-receptor antagonist conivaptan in a large cohort of brain-injured patients with acute hyponatremia. ⋯ Conivaptan given as a bolus can effectively treat acute hyponatremia in brain-injured patients.
-
Journal of critical care · Dec 2012
Cross-validation of a Sequential Organ Failure Assessment score-based model to predict mortality in patients with cancer admitted to the intensive care unit.
This study aims to validate the performance of the Sequential Organ Failure Assessment (SOFA) score to predict death of critically ill patients with cancer. ⋯ The SOFA score had good discrimination to predict ICU and hospital mortality. However, the observed underestimation of ICU deaths and unsatisfactory goodness-of-fit test of the model in surgical patients to indicate calibration of the score to predict ICU mortality is advised in this group.