Journal of critical care
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Mechanical ventilation (MV) predisposes patients to numerous complications, which increases with longer durations of treatment. Identifying individuals more likely to require prolonged MV (PMV) may alter ventilation strategies or potentially minimize the duration of therapy and its associated complications. Our aim was to identify clinical variables at the time of intubation that could identify individuals who will require PMV. ⋯ The novel predictive model, using Intubation in the ICU, Tachycardia, Renal dysfunction, Acidemia, elevated Creatinine, and a decreased HCO3, was highly specific in identifying patients who subsequently required PMV support and performed better than Acute Physiology Age Chronic Health Evaluation III.
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Journal of critical care · Oct 2013
Relationship between plasma high-mobility group box-1 levels and clinical outcomes of ischemic stroke.
High-mobility group box-1 (HMGB1) is regarded as a central mediator of inflammation and involved in many inflammatory diseases. This study aimed to investigate impact of plasma HMGB1 level on 1-year clinical outcomes of ischemic stroke. ⋯ Plasma HMGB1 level represents a novel biomarker for predicting 1-year clinical outcomes of ischemic stroke.
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Journal of critical care · Oct 2013
Editorial Comment LetterI-TRACH, you-TRACH, we all-TRACH for….?
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Journal of critical care · Oct 2013
Multicenter StudyDiscussion of treatment trials in intensive care.
This study aimed to characterize whether and how the option of a treatment trial is discussed with surrogates in intensive care units. ⋯ In this cohort of critically ill patients, trials were infrequently and incompletely discussed. Additional work is needed to improve communication about treatment trials and evaluate their impact on patient and family outcomes.