Journal of critical care
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Journal of critical care · Aug 2014
Usefulness of interleukin 6 levels in the cerebrospinal fluid for the diagnosis of bacterial meningitis.
Interleukin 6 (IL-6) is a proinflammatory cytokine produced during infections. We hypothesized that IL-6 levels in the cerebrospinal fluid (CSF) would be elevated in bacterial meningitis and useful for diagnosing and predicting neurologic outcomes. ⋯ Measurement of the CSF IL-6 level is useful for diagnosing bacterial meningitis.
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Journal of critical care · Aug 2014
The prognostic and risk-stratified value of heart-type fatty acid-binding protein in septic patients in the emergency department.
To evaluate the prognostic and risk-stratified ability of heart-type fatty acid-binding protein (H-FABP) in septic patients in the emergency department (ED). ⋯ Heart-type fatty acid-binding protein was helpful for prognosis and risk stratification of septic patients in the ED.
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Journal of critical care · Aug 2014
Microcirculatory perfusion derangements during continuous hemofiltration with fixed dose of ultrafiltration in stabilized intensive care unit patients.
Acute kidney injury (AKI) is a well-known complication in critically ill patients. Little is known about the timing and the ultrafiltration dose after initial resuscitation. In vivo microscopy of the microcirculation has been suggested as alternative for the assessment of volume status. Previous studies contribute to the understanding that intravascular hypovolemia is reflected by microcirculatory blood flow changes not detected by conventional methods. The aim of our study was to assess microcirculatory blood flow changes during negative fluid balance ultrafiltration in patients with oliguric AKI. ⋯ Microcirculatory blood flow is not altered by reduced substitution during renal replacement therapy.
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Journal of critical care · Aug 2014
Clinical results of early stabilization of spine fractures in polytrauma patients.
The purpose of study was to evaluate the clinical results of early stabilization of spine fractures in polytrauma patients. ⋯ Polytrauma patients whose spine fractures were stabilized within 72 hours had better clinical outcomes than those with late stabilization. In addition, more severely injured patients (ISS, ≥26) benefited more from early stabilization.
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Journal of critical care · Aug 2014
Verifying a medical protocol with temporal graphs: The case of a nosocomial disease.
Our contribution focuses on the implementation of a formal verification approach for medical protocols with graphical temporal reasoning paths to facilitate the understanding of verification steps. ⋯ The proposed approach allows for the visual modeling of temporal reasoning and a formalization of knowledge that can assist in the diagnosis and treatment of nosocomial infections and some clinical problems. This is the first time that one emphasizes the temporal situation modeling in conceptual graphs. It will also deliver a formal verification method for clinical guideline analyses.