Journal of critical care
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Journal of critical care · Apr 2016
Early central diabetes insipidus: An ominous sign in post-cardiac arrest patients.
Central diabetes insipidus (CDI) after cardiac arrest is not well described. Thus, we aim to study the occurrences, outcomes, and risk factors of CDI of survivors after out-of-hospital cardiac arrest (OHCA). ⋯ All patients diagnosed with CDI had poor neurologic outcomes, and occurrence of CDI was associated with mortality. Central diabetes insipidus patients with death or brain death had earlier occurrence of CDI and more maximum urine output.
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Journal of critical care · Apr 2016
Review Meta AnalysisThe effects of chlorhexidine gluconate bathing on health care-associated infection in intensive care units: A meta-analysis.
The purpose was to assess the effects of chlorhexidine gluconate (CHG) bathing on health care-associated infections among critically ill patients. ⋯ Daily CHG bathing was associated with reduced risks of acquiring CLABSI, MRSA, and VRE. A prolonged intervention period and concomitant nasal antibiotic use were associated with lower risks of MRSA acquisition.
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Journal of critical care · Apr 2016
ReviewBarbiturates for the treatment of alcohol withdrawal syndrome: A systematic review of clinical trials.
To perform a systematic review of the clinical trials concerning the use of barbiturates for the treatment of acute alcohol withdrawal syndrome (AWS). ⋯ Although the evidence is limited, based on our findings, adding phenobarbital to a BZD-based regimen is a reasonable option, particularly in patients with BZD-refractory AWS.
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Journal of critical care · Apr 2016
ReviewSurvival benefits of dexmedetomidine used for sedating septic patients in intensive care setting: A systematic review.
The aim of this systematic review was to evaluate the effectiveness and safety of dexmedetomidine used for sedation of patients with sepsis. ⋯ In a small group of studies of patients with sepsis, dexmedetomidine improved short-term mortality compared with other sedatives without affecting the intensive care unit length of stay. Further studies are warranted to confirm whether using this particular agent improves sepsis outcomes in comparison to other commonly used sedating agents.