Journal of critical care
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Journal of critical care · Oct 2017
Serum lactate dehydrogenase is predictive of persistent organ failure in acute pancreatitis.
Elevated serum lactate dehydrogenase (LDH) has been reported in a serious of clinical diseases. However, the relationship between LDH and the incidence of persistent organ failure (POF) in acute pancreatitis (AP) has not been characterized. ⋯ Our results indicate that serum LDH on admission is independently associated with POF in AP and may serve as a potential prognostic factor.
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Journal of critical care · Oct 2017
A comparison of pre ICU admission SIRS, EWS and q SOFA scores for predicting mortality and length of stay in ICU.
The 2015 sepsis definitions suggest using the quick SOFA score for risk stratification of sepsis patients among other changes in sepsis definition. Our aim was to validate the q sofa score for diagnosing sepsis and comparing it to traditional scores of pre ICU admission sepsis outcome prediction such as EWS and SIRS in our setting in order to predict mortality and length of stay. ⋯ In conclusion, we find that in our setting, EWS is better than SIRS and q SOFA for predicting mortality and perhaps length of stay as well. The q Sofa score remains validated for diagnosis of sepsis.
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Journal of critical care · Oct 2017
Management of ventilator associated pneumonia with a new antibiotic adjuvant entity (ceftriaxone+sulbactam+disodium edetate) - A novel approach to spare carbapenems.
Ventilator associated pneumonia (VAP) is one of the most serious nosocomial infections in Intensive Care Unit (ICU). The aim of this study was to evaluate a new approach to spare the carbapenems for the management of patients diagnosed with VAP due to Acinetobacter baumannii (A. baumannii). ⋯ Clinical assessment with microbial eradication and pharmaco-economic evaluation clearly shows benefits in using AAE empirically in the management of A. baumannii infected VAP cases.
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Journal of critical care · Oct 2017
The association between red cell distribution width and poor outcomes in hospitalized patients with influenza.
To examine an association between red blood cell distribution width (RDW) and the prognosis of influenza patients. ⋯ RDW>14.5% was a predictor of severe hospital complications in patients with influenza.
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Journal of critical care · Oct 2017
U.S. drug shortages for medications used in adult critical care (2001-2016).
We describe trends in U.S. shortages impacting critical care drugs from 2001 to 2016. ⋯ Although the number of new shortages peaked in 2011 and is now declining, there remain a substantial number of active shortages impacting critical care drugs.